Trouver un essai clinique à L’Hôpital d’Ottawa

Les essais cliniques nous permettent de déterminer la sécurité et l’efficacité de traitements, de dispositifs et d’actes médicaux. Votre participation à un essai clinique ne vous garantit pas de bénéfice personnel, mais elle contribuera certainement à l’acquisition de nouvelles connaissances qui bénéficieront à d’autres personnes.

Comment utiliser l’outil :

  • Tapez dans le champ de recherche le nom d’une maladie ou d’un problème de santé en particulier.
  • Apportez les résultats de votre recherche à votre prochain rendez-vous pour les montrer à votre équipe de soins.
  • Si votre équipe de soins juge que vous pourriez être admissible à un essai, et si vous le souhaitez, elle vous recommandera auprès de l’équipe de recherche concernée.

Remarques :

  • Nous ne pouvons pas garantir une réponse de la personne nommée dans la colonne Contact. Présentez plutôt les renseignements que vous avez trouvés à votre équipe de soins lors de votre prochain rendez-vous.
  • Les renseignements fournis dans le tableau ci-dessous sont tirés de, une ressource de la U.S. National Library of Medicine offerte en anglais seulement.

NCT04417023B3 for NMD: Bench to Bedside and Back (NCT04417023)Neuromuscular
NCT03936127Comparison of a Novel Transperineal Targeted Fusion Biopsy System to Conventional Transrectal Targeted Fusion Biopsy (NCT03936127)Prostate,
NCT04136496Evaluation of a Novel Axillary Lymph Node Ink Localization Technique: A Feasibility Study (NCT04136496)Breast Cancer,Axillary
NCT05264285Mitochondrial Health and Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients (NCT05264285)Acute Kidney Injury (AKI)
NCT03746925Comparing Short-term Outcomes After Direct Anterior and SuperPATH Hip Arthroplasty Approaches (NCT03746925)Arthroplasty, Replacement,
NCT04871412The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage II (NCT04871412)Lung Cancer,Gastric Cancer,Esophageal
NCT05468281RAFF5 Proposal: Improve the Quality and Safety of Patients Seen in the Emergency Department for Acute Atrial Fibrillation and Flutter (NCT05468281)Atrial Fibrillation,Atrial
NCT05496309Causes and Mechanisms of Space Hemolysis at High Altitudes (NCT05496309)Anemia,
NCT05852262High-dose Cephalexin for Cellulitis (HI-DOCC) (NCT05852262),
NCT05762601Cellular precOnditioning for Post-Surgical Myocardial Ischemic Complications - Observational Study (NCT05762601)Cardiac Complication,Myocardial Infarction,Myocardial Ischemia,Myocardial InjuryRecruiting 
NCT05019963Enhancing COVID Rehabilitation With Technology (NCT05019963)
NCT04392921Prophylaxis for Patients at Risk to Eliminate Post-operative Atrial Fibrillation (NCT04392921)Atrial
NCT05169112Impact of Hormonal Therapy on Prostate Cancer Recurrence After Radical Prostatectomy (NCT05169112)Prostate
NCT03787589Exercise in Patients With End Stage Kidney Disease (NCT03787589)Renal FailureRecruiting 
NCT04221295The PREPARE Trial: Exercise Before Surgery to Improve Recovery in Older People With Frailty (NCT04221295)Frailty,Surgery--Complications,Disability
NCT03677713Nasal Packing Following Endoscopic Endonasal Pituitary Resection (NCT03677713)Pituitary
NCT02966886TSA Techniques in Glenohumeral OA (NCT02966886)Osteoarthritis,
NCT05206747Ottawa Sunglasses at Night for Mania Study (NCT05206747)Mania,Sleep,Bipolar
NCT04921137Evaluating Harms and Benefits of Endocrine Therapy in Patients ≥70 Years of Age With Lower Risk Breast Cancer (NCT04921137)Breast
NCT04633525Defining Optimum Cup Orientation for Hip Replacements Taking Into Account the Individual's Anatomy and Movement Patterns (NCT04633525)Hip Arthritis,Hip
NCT03959709Pre-pectoral Versus Sub-pectoral Implant Placement in Immediate Breast Reconstruction (NCT03959709)Mastectomy,Breast CancerRecruiting 
NCT03031873Evaluation of Susceptibility-weighted Magnetic Resonance Imaging and 4d-time-resolved Magnetic Resonance Angiography in Brain Arteriovenous Malformations (NCT03031873)Arteriovenous
NCT00800059Total Marrow Irradiation & Autologous Stem Cell Transplantation for Relapsed or Refractory Myeloma (NCT00800059)Multiple
NCT05487274TSA v RSA in Osteoarthritic Shoulders With Greater Than 15 Degrees of Retroversion (NCT05487274)Osteoarthritis
NCT03809884Dietary Counseling or Potassium Supplement to Increase Potassium Intake in Patients With High Blood Pressure (NCT03809884)
NCT01799967Minimally Invasive Surgery of the Gastro-esophageal Junction (NCT01799967)Achalasia,Paraesophageal Hernia,GERD,Epiphrenic Diverticula,Zenker's DiverticulumRecruiting 
NCT05101928Ozurdex Monotherapy Trial (NCT05101928)Uveitis, Posterior,Uveitis, Intermediate,
NCT04080466Cam Type FAI is a Cause of Hip Pain in the Young Adult and a Precursor to OA (NCT04080466)Hip Dysplasia,Femoroacetabular Impingement,
NCT03663504Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon Surgery (NCT03663504)Elective Colon SurgeryRecruiting 
NCT03713255Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial (NCT03713255)Breast Cancer,Acute Pain,AnesthesiaRecruiting 
NCT04708509Extubation Advisor: Initial Implementation and Evaluation of a Novel Extubation Clinical Decision Support Tool (NCT04708509)Airway ExtubationRecruiting 
NCT02236689Comparing Arthroscopic Tennis Elbow Release With Arthroscopic Debridement (NCT02236689)Tennis ElbowRecruiting 
NCT05754528Evaluating an Endocrine Therapy Dose-frequency Escalation Strategy and Its Effects on Tolerability and Compliance (NCT05754528)Breast
NCT05753618Evaluating Omission of Granulocyte Colony-stimulating Factors in Breast Cancer Patients Receiving Paclitaxel Portion of Dose-dense Adriamycin-cyclophosphamide and Paclitaxel Chemotherapy (NCT05753618)Early-stage Breast
NCT04549207Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients Treated for Over 2 Years for Bone Metastases From Either Breast or Castration-resistant Prostate Cancer (NCT04549207)Breast Cancer,Castration-resistant Prostate CancerRecruiting 
NCT03147859Vedolizumab Treatment in Antiretroviral Drug Treated Chronic HIV Infection (NCT03147859)HIV-infection/
NCT05066347REmote Cardiac MOnitoring of At-risk SYNCope Patients After Emergency Department Discharge -RCT (NCT05066347),
NCT04781725INVINCIBLE TRIAL: Intratumoral INT230-6 in Breast Cancer (NCT04781725)Breast
NCT04661787Donation Advisor Clinical Decision Support Tool Study (NCT04661787)Organ
NCT05198869SpotLight-19 Research & Development Study (NCT05198869)ScreeningRecruiting 
NCT04671862Photobiomodulation for the Prevention of Radiation Induced Oral Mucositis (NCT04671862)Mucositis Oral,Head and Neck Cancer,Radiation,
NCT04105179How TKA Implants Affect Muscle Quality and Activity During Daily Living and Immunological Response (NCT04105179)Osteoarthritis, Knee,Inflammation KneesRecruiting 
NCT03806114Dislocation Precautions (NCT03806114)Arthroplasty, Hip Replacement,Arthroplasties, Hip Replacement,Health-Related Quality Of
NCT03100110NeuroCognitive Communicator: Safety Study (NCT03100110)Motor Neuron Disease, Amyotrophic Lateral Sclerosis,
NCT05326334THERApeutic Outcomes Related to Gut microBIOME in Glioblastoma (GBM) Patients Receiving Chemo-radiation (THERABIOME-GBM) (NCT05326334)Glioblastoma, IDH-wildtypeRecruiting 
NCT05255003STrategies for Anticoagulation in Patients With thRombocytopenia and Cancer-associated Thrombosis (NCT05255003)Cancer-associated Thrombosis,
NCT03506867A Healthy People Initiative: Building the Socio-Economic Capital of Low Income Population At-Risk for HIV and Hepatitis-C (NCT03506867)Nicotine Dependence,Substance Use
NCT04500626Hyperbaric Versus Normobaric Oxygen Therapy for COVID-19 Patients (NCT04500626),
NCT05781113A Novel Wearable Digital Biomarker for Detecting Changes in Multiple Sclerosis (MS) Condition (NCT05781113)Multiple
NCT05309226Cannabis Use in Pregnancy and Downstream Effects on Maternal and Infant Health (NCT05309226)Cannabis Use,Marijuana,
NCT04935866Optimal Brain Oxygenation in Neurologic Intensive Care Unit : The NeurO2 Study (NCT04935866)Traumatic Brain Injury,Subarachnoid Hemorrhage,Brain Injuries,Near-Infrared Spectroscopy,Intensive Care Neurological Disorder,AnemiaRecruiting 
NCT03765177CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies (NCT03765177)Acute Lymphoblastic Leukemia,Non-Hodgkin's Lymphoma,Chronic Lymphocytic,
NCT03175718INPWT on Wound Complications & Clinical Outcomes After Lower Extremity Sarcoma Surgery Preop Radiation Therapy Patients (NCT03175718)Soft-tissue Sarcoma,Wound
NCT04907279Aripiprazole Once-Monthly in Hospitalized Patients (INITIATE) (NCT04907279)Schizophrenia,Schizo Affective Disorder,Bipolar I DisorderRecruiting 
NCT04257227Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness (NCT04257227)Depressive Symptoms,Depression, Anxiety,Psychological Distress,Terminal
NCT04080934Breaststroke Swimming After Breast Cancer Treatment/Surgery as a Means of Treatment for Seroma, Lymphedema, and Chronic Arm and Chest Pain (NCT04080934)Lymphedema,Seroma,Pain, Postoperative,Pain, ChestRecruiting 
NCT04163081The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (NCT04163081)Nicotine Dependence, Cigarettes,Nicotine
NCT04228419TSA vs RSA in Glenohumeral Osteoarthritis (NCT04228419)Osteoarthritis of the ShoulderRecruiting 
NCT02975310In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps (NCT02975310)Sinusitis,Nasal
NCT04970771Solving Wellness: An Initiative to Enhance Canadian Healthcare Provider Wellness (NCT04970771)Stress,Burnout, Professional,BurnoutRecruiting 
NCT04642430COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial Fibrillation (NCT04642430)Atrial,
NCT04543110Radiation and Durvalumab Immunotherapy As Neoadjuvant Treatment for MIBC (NCT04543110)Bladder
NCT04894448Immunogenicity of COVID-19 Vaccination in PLWH (NCT04894448)HIV InfectionsRecruiting 
NCT05115617Pregnant and Lactating Individuals & Newborns COVID-19 Vaccination Prospective Cohort Study (NCT05115617)SARS-CoV2 Infection,Covid19,Vaccine Reaction,Pregnancy Related,,
NCT03949387Functional Electrical Stimulation Cycling for Managing Mobility Disability in People With Multiple Sclerosis (NCT03949387)Multiple SclerosisRecruiting 
NCT03297359WAVe Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism (NCT03297359)Cancer,Venous Thromboembolism,ObesityRecruiting 
NCT02281838The Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial II (NCT02281838)Intracerebral
NCT04549662The HepatoPancreaticoBiliary Resection Arginine Immunomodulation (PRIMe) Trial (NCT04549662)Hepatopancreaticobiliary (HPB) Malignancy,,
NCT03639064Cannabis Oil for Pain in Parkinson's Disease (NCT03639064)Parkinson DiseaseRecruiting 
NCT04319627Statins for Venous Event Reduction in Patients With Venous Thromboembolism (NCT04319627)Venous Thromboembolism,Blood Clot,Post Thrombotic
NCT03481010Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology (NCT03481010)Hip DysplasiaRecruiting 
NCT04824144Effects of Dexmedetomidine in Patients With Agitated Delirium in Palliative Care (NCT04824144)Hyperactive Delirium,Delirium of Mixed OriginRecruiting 
NCT05029063Primary Thromboprophylaxis in Patients With Malignancy and Central Venous Catheters (NCT05029063)Venous Thromboembolism,,
NCT04485195RAFF4 Trial: Vernakalant vs. Procainamide for Acute Atrial Fibrillation in the Emergency Department (NCT04485195)Atrial,
NCT03266783Comparison of Bleeding Risk Between Rivaroxaban and Apixaban for the Treatment of Acute Venous Thromboembolism (NCT03266783)Venous,
NCT03309579SAHaRA: A Randomized Controlled Trial (NCT03309579)Subarachnoid Hemorrhage,
NCT05258578Tele-BARICARE to Manage COVID-19-Related Distress (NCT05258578)Obesity,Bariatric Surgery Candidate,Mental Health Disorder,Eating
NCT04448184Platelet Transfusions in Hematopoietic Stem Cell Transplantation (The PATH III Trial) (NCT04448184)Hematologic
NCT05809999IBD Neoplasia Surveillance RCT (NCT05809999)Colonic Neoplasms,Inflammatory Bowel Diseases,DysplasiaRecruiting 
NCT03103932Biomarker Guided Discharge of Heart Failure Patients (NCT03103932)Heart Failure; With DecompensationRecruiting 
NCT04224974Emotion and Symptom-Focused Engagement Trial for Individuals With Acute Leukemia (NCT04224974)Acute LeukemiaRecruiting 
NCT04318665Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI Study) (NCT04318665)Traumatic Brain InjuryRecruiting 
NCT05605509RP-6306 in Patients With Advanced Cancer (NCT05605509)Advanced CancerRecruiting 
NCT05096195PRevEnting FracturEs in REnal Disease 1 (NCT05096195)Kidney Diseases,Dialysis; Complications,Fragility Fracture,Chronic Kidney Disease-Mineral and Bone
NCT04803747A Trial of a Hospital Policy of Tranexamic Acid Use to Reduce Transfusion in Major Non-cardiac Surgery (NCT04803747)Major Non-cardiac,
NCT02869802Prospectively Defining Metastatic Pancreatic Ductal Adenocarcinoma Subtypes by Comprehensive Genomic Analysis (NCT02869802)Cancer,Pancreatic CancerRecruiting 
NCT04304651Screening for Occult Malignancy in Patients With Unprovoked Venous Thromboembolism (NCT04304651)Embolism and,
NCT02821013Duration of Anti-PD-1 Therapy in Metastatic Melanoma (NCT02821013)Unresectable/Metastatic MelanomaRecruiting 
NCT03850847Understanding Decision Making in the Intensive Care Unit: a National Study (NCT03850847)Organ DonationRecruiting 
NCT04624477Active Surveillance and Surgery Outcomes in Low Risk Papillary Thyroid Cancer (NCT04624477)Papillary Thyroid Cancer,Papillary Thyroid Carcinoma,Papillary Microcarcinoma of the ThyroidRecruiting 
NCT05601440Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer (NCT05601440)Breast CancerRecruiting 
NCT03260478HEMOglobin Transfusion Threshold in Traumatic Brain Injury OptimizatioN: The HEMOTION Trial (NCT03260478)Traumatic Brain Injury,TransfusionRecruiting 
NCT05371808Economic Analysis of Early vs Delayed Therapy in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: (NCT05371808)Chronic Lymphocytic Leukemia,Small Lymphocytic LymphomaRecruiting 
NCT05707208A Randomized, Controlled Study of Repeat Dose Sustained Release Lidocaine for Treatment of Chronic Scrotal Pain (NCT05707208)Chronic
NCT04260802A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers (NCT04260802)Cancer,Neoplasms,Metastatic Cancer,Triple Negative Breast Cancer,Gastric Cancer,Cervical Cancer,Ovarian Cancer,Hepatocellular Carcinoma,Squamous Cell Carcinoma of Head and Neck,Urothelial Carcinoma,Urothelial Neoplasm,Non Small Cell Lung Cancer,Renal Cell Carcinoma,Locally Advanced Solid Tumor,Locally Advanced Malignant Neoplasm,Squamous Cell Carcinoma,Sarcoma,Merkel Cell Carcinoma,Bladder
NCT04180722Transition to LIVE (Long-term In Home Ventilation Engagement) Study (NCT04180722)Long-term Ventilation at
NCT02999022Lithium for Fracture Treatment: a Double Blind Randomized Controlled Trial (LiFT) (NCT02999022),
NCT05306327Neurologic Physiology After Removal of Therapy (NeuPaRT) (NCT05306327)Determination of DeathRecruiting 
NCT05899101The Impact of Opioid and Cannabis Exposure on Fetal Growth (NCT05899101)Pregnancy Related,Substance Use,Fetal Growth Retardation,Placenta DiseasesRecruiting 
NCT04794569Tinzaparin Lead-In to Prevent the Post-Thrombotic Syndrome (NCT04794569)Deep Vein Thrombosis,Post Thrombotic,
NCT04263038Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism (NCT04263038)Pulmonary Embolism,Embolism,Embolism and Thrombosis,Lung Diseases,Cardiovascular Diseases,Respiratory Tract Diseases,Venous Thromboembolism,Anticoagulant-induced Bleeding,BleedingRecruiting 
NCT04223505Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus (NCT04223505)Atrial FibrillationRecruiting 
NCT04330690Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial (NCT04330690),,
NCT04743765HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial (NCT04743765)Hip Fractures,Myocardial
NCT05171075A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE (NCT05171075)Venous Thromboembolism,Deep Venous Thrombosis,Pulmonary EmbolismRecruiting 
NCT04702945Canadian COVID-19 Emergency Department Registry (NCT04702945)Covid-19Recruiting 
NCT03385655Prostate Cancer Biomarker Enrichment and Treatment Selection (NCT03385655)Prostate CancerRecruiting 
NCT05032495Patient Engagement Study to Evaluate the Use of Biological Therapies for Cardiac Arrhythmias (NCT05032495)ArrythmiaRecruiting 
NCT05176639A Safety, Tolerability and Efficacy Study of VRDN 001 in Healthy Volunteers and Persons With Thyroid Eye Disease (TED) (NCT05176639)Thyroid Eye DiseaseRecruiting 
NCT05913687Automated Imaging Differentiation of Parkinsonism (NCT05913687)Parkinson Disease,Multiple System Atrophy, Parkinson Variant,Progressive Supranuclear
NCT05716334Biosimilars of Rituximab in ANCA-associated Vasculitis Compared to the Originator (NCT05716334)ANCA-associated Vasculitis,Granulomatosis With Polyangiitis,Microscopic PolyangiitisRecruiting 
NCT02960087Phase II High Dose Brachytherapy and Low Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer (NCT02960087)Prostate CarcinomaRecruiting 
NCT04564079An Observational Study to Evaluate the Clinical Utility of the Oncomine Precision Assay Within the Exactis Network (NCT04564079)
NCT05840224Study of GS-4528 in Adults With Solid Tumors (NCT05840224)Solid TumorRecruiting 
NCT03718260PSMA-PET Registry for Recurrent Prostate Cancer (NCT03718260)Recurrent Prostate
NCT05466838PERT to Improve Quality of Life in Patients Undergoing Pancreaticoduodenectomy: A Pilot Randomized Controlled Trial (NCT05466838)Pancreatic InsufficiencyRecruiting 
NCT04580225Randomized Comparison of PARtial Wrist Fusion With or Without Triquetral Excision (PARTE) (NCT04580225)Wrist Arthritis,Wrist Arthropathy,Scapholunate Advanced Collapse,Scaphoid Nonunion,Post-traumatic; Arthrosis,Arthritis,Musculoskeletal Diseases,Joint
NCT05955924Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients - Pivotal Trial (NCT05955924)Non-melanoma Skin Cancer,Carcinoma, Squamous Cell,Carcinoma, Basal Cell,Keratinocyte CarcinomaRecruiting 
NCT03261102TDM Guided Early Optimization of ADAL in Crohn's Disease (NCT03261102)Crohn Disease,Drug Monitoring,Inflammatory Bowel
NCT04415060SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival (NCT04415060)Covid19,Hypoxic Respiratory,
NCT04472910GATA6 Expression as a Predictor of Response to Peri-Operative Chemotherapy in Resectable Pancreatic Adenocarcinoma (NCT04472910)Resectable Pancreatic CancerRecruiting 
NCT05137119Staphylococcus Aureus Network Adaptive Platform Trial (NCT05137119)Staphylococcus Aureus BacteremiaRecruiting 
NCT03070522Prednisone in Cystic Fibrosis Pulmonary Exacerbations (NCT03070522)Cystic Fibrosis Pulmonary,
NCT05892666The Right Care, for the Right Patient, at the Right Time, by the Right Provider: A Value-based Comparison of the Management of Ambulatory Patients With Acute Health Concerns in walk-in Clinics, Primary Care Physician Practices and Emergency Departments (NCT05892666)Ambulatory Care,Emergency Services, Hospital,Quality of Care,
NCT04035005A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (NCT04035005)Multiple Sclerosis, Primary ProgressiveRecruiting 
NCT05171049A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE (NCT05171049)Venous Thromboembolism,Deep Venous Thrombosis,Pulmonary EmbolismRecruiting 
NCT05487235A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors (NCT05487235)Advanced Solid Tumors,Metastatic Solid TumorsRecruiting 
NCT04449874A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation (NCT04449874)Non-Small Cell Lung Cancer,Colorectal Cancer,Advanced Solid TumorsRecruiting 
NCT02735707Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (NCT02735707)Community-acquired Pneumonia, Influenza, COVID-19Recruiting 
NCT03833024The MUFFIN-PTS Trial (NCT03833024)Post-Thrombotic,
NCT03559114PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST) (NCT03559114)Traumatic Brain,
NCT02675569ACCESS HD: Comparing Catheters to Fistulas in Elderly Patients Starting Hemodialysis (NCT02675569)End-stage Kidney,
NCT04558593Surveillance of Complex Renal Cysts - The SOCRATIC Study (NCT04558593)Complex Renal CystRecruiting 
NCT04182776Fragility Fractures of the Pelvis (FFP) (NCT04182776)Pelvic FractureRecruiting 
NCT03569826Canadian Network for Autoimmune Liver Disease (NCT03569826)Primary Bilary Cirrhosis (PBC),Autoimmune Hepatitis,Overlap,
NCT05395819Clinical Evaluation of Reverse Versus Anatomic Shoulder Arthroplasty Techniques in the Treatment of Osteoarthritis (NCT05395819)Shoulder OsteoarthritisRecruiting 
NCT05032196Study of WVE-003 in Patients With Huntington's Disease (NCT05032196)Huntington
NCT04874038Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN) (NCT04874038)Post-mastectomy Pain Syndrome,Breast Cancer,Pain, Postoperative,Pain, ChronicRecruiting 
NCT05428735The DRAGON 2 Trial (NCT05428735)Colorectal Cancer Liver Metastases (CRLM),Small Future Liver Remnant (FLR)Recruiting 
NCT04624906Bendamustine, Rituximab and Acalabrutinib in Waldenstrom's Macroglobulinemia (NCT04624906)Waldenstrom MacroglobulinemiaRecruiting 
NCT03573089Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE) (NCT03573089)Kidney Failure, Chronic,
NCT03589326A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia (NCT03589326)Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
NCT01574053Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort (NCT01574053)Huntington's
NCT03944798Surveillance AFter Extremity Tumor surgerY (NCT03944798)Soft Tissue Sarcoma,Lung MetastasesRecruiting 
NCT04683848Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury (NCT04683848)Spinal Cord InjuryRecruiting 
NCT02355171Personalize My Treatment (PMT) Registry (NCT02355171)
NCT03838718REtroperitoneal SArcoma Registry: an International Prospective Initiative (NCT03838718)Retroperitoneal
NCT04335292Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer With Osimertinib Third-line Rechallenge (NCT04335292)Non-Small Cell Lung CancerRecruiting 
NCT03715478Multi-Center Study of GSK2857916 in Combination With Pomalidomide and Dex (NCT03715478)Relapsed and/or Refractory Multiple MyelomaRecruiting 
NCT04521413Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies (NCT04521413)Advanced Solid MalignanciesRecruiting 
NCT02906943Ontario-wide Cancer TArgeted Nucleic Acid Evaluation (NCT02906943)Breast Cancer,Lung Cancer,Colorectal Cancer,Melanoma,Gynecological Cancer,Genitourinary Cancer,Pancreatobiliary Cancer,Gastrointestinal Cancer,Head and Neck Cancer,Rare Cancer,Unknown Primary,
NCT05151172EndovaSCular TreAtment to imProve outcomEs for Medium Vessel Occlusions (ESCAPE-MeVO Trial) (NCT05151172)Acute Ischemic
NCT03860883Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (NCT03860883)Cutaneous Melanoma, Stage
NCT03297606Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR) (NCT03297606)Lymphoma, Non-Hodgkin,Multiple Myeloma,Advanced Solid TumorsRecruiting 
NCT05180097Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for Relapsed/Refractory Hodgkin Lymphoma (NCT05180097)Hodgkin LymphomaRecruiting 
NCT02436707Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma (NCT02436707)LymphomaRecruiting 
NCT00819208Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer (NCT00819208)Anxiety Disorder,Cognitive/Functional Effects,Colorectal Cancer,Depression,Fatigue,Psychosocial Effects of Cancer and Its Treatment,Sleep Disorders,ExcerciseRecruiting 
NCT03784755Local Ablative Therapy For Hormone Sensitive Oligometastatic Prostate Cancer (NCT03784755)Prostate Cancer MetastaticRecruiting 
NCT04675294Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03) (NCT04675294)Head and Neck Cancer,Head and Neck Squamous Cell CarcinomaRecruiting 
NCT03151629International Registry for Men With Advanced Prostate Cancer (IRONMAN) (NCT03151629)Prostate CancerRecruiting 
NCT05132582A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer (NCT05132582)HER2 Positive Breast CancerRecruiting 
NCT04151342CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS) (NCT04151342)Cancer,Malignancies Multiple,Malignant Solid Tumor,Cancer, Therapy-Related,Molecular Sequence Variation,Genetic Alteration,Gene Fusion,Receptor Tyrosine Kinase Gene Mutation,RTK Family Gene Mutation,Ras (Kras or Nras) Gene MutationRecruiting 
NCT05229900A Study of SGN-ALPV in Advanced Solid Tumors (NCT05229900)Ovarian Neoplasms,Endometrial Neoplasms,Carcinoma, Non-Small-Cell Lung,Stomach Neoplasms,Gastroesophageal Junction Carcinoma,Uterine Cervical Neoplasms,Testicular NeoplasmsRecruiting 
NCT02468024JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer (NCT02468024)Non-Small Cell Lung,
NCT05199272A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies (NCT05199272)Solid Tumor,Clear Cell Renal Cell Carcinoma,Epithelial Ovarian Cancer,Fallopian Tube Cancer,Primary Peritoneal Carcinoma,Neuroendocrine Tumors,MSI-H Cancer,Cancer With A High Tumor Mutational Burden,Extensive-stage Small-cell Lung CancerRecruiting 
NCT04680442Safety of Continuing HER-2 Directed Therapy in Overt Left Ventricular Dysfunction (NCT04680442)Breast Cancer,Heart
NCT03948074Cannabis For Cancer-Related Symptoms (NCT03948074)Pain,Nausea,Anxiety,Sleep
NCT03778502DOAC in Unusual Site Venous Thrombosis (NCT03778502)Splanchnic Vein Thrombosis,Cerebral Vein Thrombosis,Ovarian Vein Thrombosis,Renal Vein Thrombosis,Retinal Vein ThrombosisRecruiting 
NCT03020303Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease (NCT03020303)Endstage Renal
NCT04650581Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive (ER+) Breast Cancer Following Progression on First Line CDK 4/6 Inhibitor and Aromatase Inhibitor (NCT04650581)Breast CancerRecruiting 
NCT03127631A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients (NCT03127631)Prostate Cancer,Cardiovascular
NCT03496883Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial (NCT03496883)Intracerebral
NCT04853576A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY) (NCT04853576)Sickle Cell Disease,HemoglobinopathiesRecruiting 
NCT04401475A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 + SOC vs. Placebo + SOC in Adult Hospitalized Patients With COVID-19 (NCT04401475)COVID-19,ARDSRecruiting 
NCT03847649A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Related Toxicity - Substudy B: For Continued Treatment (+/- Tremelimumab) of Patients Previously Enrolled to Completed CCTG Studies (NCT03847649)CancerRecruiting 
NCT05364749Selective CT for Anticoagulated Head Injured Patients (NCT05364749)Head Injury,Traumatic Brain Injury,Intracranial Hemorrhage, Traumatic,Blunt Head InjuryRecruiting 
NCT05376891Met Non Small Cell Cancer Registry (MOMENT) (NCT05376891)CancerRecruiting 
NCT03419689Study Looking at Biomarkers in Ovarian Cancer (NCT03419689)Gynecologic
NCT03674307Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates (NCT03674307)Cardiovascular Diseases,End Stage Renal Disease,Kidney Transplantation,Dialysis Related,
NCT05382299Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Metastatic Triple-Negative Breast Cancer (NCT05382299)Triple Negative Breast Cancer,PD-L1 NegativeRecruiting 
NCT05382286Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer (NCT05382286)Triple Negative Breast Cancer,PD-L1 PositiveRecruiting 
NCT03642587Canadian Sudden Cardiac Arrest Network (NCT03642587)Sudden Cardiac Death,Sudden Cardiac ArrestRecruiting 
NCT05581004A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors (NCT05581004)Locally Advanced or Metastatic Solid Tumors,NSCLC,HNSCC,Melanoma,TNBC,Esophageal Cancer,Gastric Cancer,Cervical Cancer,Urothelial Carcinoma,Clear Cell RCC,HCCRecruiting 
NCT04835805A Study to Evaluate the Safety and Activity of Belvarafenib as a Single Agent and in Combination With Either Cobimetinib or Cobimetinib Plus Nivolumab in Patients With NRAS-mutant Advanced Melanoma. (NCT04835805)MelanomaRecruiting 
NCT05325866A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (NCT05325866)Solid TumorsRecruiting 
NCT04471844Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM (NCT04471844)Glioblastoma
NCT05388669A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer (NCT05388669)Advanced or Metastatic Non-small Cell Lung CancerRecruiting 
NCT05445778Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer (GLORIOSA) (NCT05445778)Ovarian Cancer,Peritoneal Cancer,Fallopian Tube
NCT05052801Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (NCT05052801)Gastric Cancer,Gastroesophageal Junction AdenocarcinomaRecruiting 
NCT05379595A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer (NCT05379595)Advanced or Metastatic Colorectal CancerRecruiting 
NCT05269355A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS) (NCT05269355)LeiomyosarcomaRecruiting 
NCT05327530A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley) (NCT05327530)Locally Advanced or Metastatic Urothelial CarcinomaRecruiting 
NCT04894591To Assess the Effectiveness and Safety of Zepzelca in Adult Patients With Extensive Stage Small Cell Lung Cancer (SCLC) (NCT04894591)Extensive-stage Small-cell Lung CancerRecruiting 
NCT03968393Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Perioperative AF After Noncardiac Surgery (NCT03968393)Stroke,Atrial FibrillationRecruiting 
NCT03950076EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF) (NCT03950076)Intracranial Hemorrhages,Atrial FibrillationRecruiting 
NCT05049798A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice (NCT05049798)Arthritis, PsoriaticRecruiting 
NCT04951622A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis (NCT04951622)Myasthenia GravisRecruiting 
NCT05054140Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis (NCT05054140)Multiple SclerosisRecruiting 
NCT04467905ReVeRA-201: Etripamil in Atrial Fibrillation, Phase 2 (NCT04467905)Atrial FibrillationRecruiting 
NCT05650632A Study to Assess Adverse Events of Intravenously (IV) Infused ABBV-383 in Adult Participants With Relapsed or Refractory Multiple Myeloma (NCT05650632)Multiple MyelomaRecruiting 
NCT04468984Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis (NCT04468984)Myelofibrosis (MF)Recruiting 
NCT04340141Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer (NCT04340141)Pancreatic Adenosquamous Carcinoma,Resectable Pancreatic Adenocarcinoma,Pancreatic CancerRecruiting 
NCT04477785PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort (NCT04477785)Parkinson DiseaseRecruiting 
NCT04045587International Severe Asthma Registry: Canadian Cohort (NCT04045587)Severe
NCT04657081Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML) (NCT04657081)Acute Myeloid LeukemiaRecruiting 
NCT04191499A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Patients With PIK3CA-Mutant, Hormone Receptor-Positive, Her2-Negative, Locally Advanced or Metastatic Breast Cancer (NCT04191499)Breast CancerRecruiting 
NCT05085366A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age (NCT05085366)Cytomegalovirus InfectionRecruiting 
NCT04295538Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI) (NCT04295538)Spinal Cord Injury (SCI)Recruiting 
NCT04529122A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test (NCT04529122)Solid TumoursRecruiting 
NCT05217446A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer (NCT05217446)Metastatic Colorectal CancerRecruiting 
NCT05546476Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15 (NCT05546476)Non-small Cell Lung Cancer,Pancreatic Cancer,Colorectal Cancer,Loss of Appetite,Fatigue,CachexiaRecruiting 
NCT04589845Tumor-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study (NCT04589845)Solid TumorsRecruiting 
NCT05646862A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy (NCT05646862)Breast CancerRecruiting 
NCT05050942A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With GEP-NET (NCT05050942)Gastro-enteropancreatic Neuroendocrine TumorRecruiting 
NCT04031677Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma (NCT04031677)Retroperitoneal Sarcoma,Liposarcoma,LeiomyosarcomaRecruiting 
NCT05573555TACTIVE-U: A Study to Learn About the Study Medicine (Called ARV-471) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B) (NCT05573555)Breast CancerRecruiting 
NCT05355701A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors. (NCT05355701)Melanoma,Colorectal Cancer,Non-Small-Cell Lung Cancer,Thyroid Cancer,GliomaRecruiting 
NCT05090566MagnetisMM-4: Umbrella Study of Elranatamab (PF-06863135) in Combination With Anti-Cancer Treatments in Multiple Myeloma (NCT05090566)Multiple MyelomaRecruiting 
NCT05548127TACTIVE-U: A Study to Learn About the Study Medicine (Called ARV-471) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A) (NCT05548127)Breast CancerRecruiting 
NCT05538130A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors (NCT05538130)Melanoma,Glioma,Thyroid Cancer,Non-Small Cell Lung Cancer,Malignant Neoplasms,Brain Neoplasms,Colorectal CancerRecruiting 
NCT05587296A Study to Learn More About How Well Elinzanetant Works and How Safe it is Compared to Placebo for the Treatment of Hot Flashes Caused by Anti-cancer Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer (NCT05587296)Vasomotor Symptoms Caused by Adjuvant Endocrine Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer,Hot FlashesRecruiting 
NCT04728893Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003) (NCT04728893)Hematologic Malignancies,Waldenstroms Macroglobulinaemia,Non-Hodgkins Lymphoma,Chronic Lymphocytic LeukaemiaRecruiting 
NCT03924869Efficacy and Safety Study of Stereotactic Body Radiotherapy (SBRT) With or Without Pembrolizumab (MK-3475) in Adults With Unresected Stage I or II Non-Small Cell Lung Cancer (NSCLC) (MK-3475-867/KEYNOTE-867) (NCT03924869)Non-Small Cell Lung CancerRecruiting 
NCT03564691Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001) (NCT03564691)NeoplasmsRecruiting 
NCT04633655International CIPN Assessment and Validation Study (NCT04633655)Chemotherapy-induced Peripheral Neuropathy,Quality of
NCT04548661Clinical Evaluation of Adults Undergoing Elective Surgery Utilizing Intraoperative Incisional Wound Irrigation (NCT04548661)Surgical Site
NCT05481151A Study to Assess Efficacy, Safety, and Tolerability of P1101 in Adult Patients With PV (NCT05481151)Polycythemia
NCT04513717Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial (NCT04513717)Metastatic Malignant Neoplasm in the Bone,Prostate Adenocarcinoma,Stage III Prostate Cancer AJCC v8,Stage IIIA Prostate Cancer AJCC v8,Stage IIIB Prostate Cancer AJCC v8,Stage IIIC Prostate Cancer AJCC v8,Stage IVA Prostate Cancer AJCC v8Recruiting 
NCT04269902Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study (NCT04269902)Chronic Lymphocytic Leukemia,Small Lymphocytic LymphomaRecruiting 
NCT03233191Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer (NCT03233191)Breast ScreeningRecruiting 
NCT03488693Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer (NCT03488693)Breast CancerRecruiting 
NCT04700124Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304) (NCT04700124)Muscle Invasive Bladder CancerRecruiting 
NCT01864096The Metformin Active Surveillance Trial (MAST) Study (NCT01864096)Prostate CancerRecruiting 
NCT03833167Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630) (NCT03833167)Carcinoma, Squamous CellRecruiting 
NCT04210115Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975) (NCT04210115)Esophageal Squamous Cell Carcinoma (ESCC),Gastroesophageal Junction Carcinoma (GEJC),Esophageal Adenocarcinoma (EAC)Recruiting 
NCT04635891Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD) (NCT04635891),
NCT03969953Treatment of Cardiovascular Disease With Low Dose Rivaroxaban in Advanced Chronic Kidney Disease (NCT03969953)Chronic Kidney Diseases,Dialysis-dependent Kidney Failure,Cardiovascular DiseaseRecruiting 
NCT03969992A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFact (NCT03969992)Respiratory Distress Syndrome in Premature InfantRecruiting 
NCT04586023Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS) (NCT04586023)Relapsing Multiple SclerosisRecruiting 
NCT05665595A Study of Adjuvant Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab for Resected High-Risk Melanoma in Participants With High-Risk Stage II-IV Melanoma (MK-7684A-010/KEYVIBE-010) (NCT05665595)MelanomaRecruiting 
NCT05686070A Study to Test Asundexian to Prevent a Clot-related Stroke in Participants After an Acute Ischemic Stroke or High-risk TIA/Mini-stroke (Transient Ischemic Attack) (NCT05686070)Prevention of Ischemic Stroke,Acute Non-cardioembolic Ischemic Stroke,High-risk Transient Ischemic AttackRecruiting 
NCT04167527Endovascular Therapy for Low NIHSS Ischemic Strokes (NCT04167527)Cerebral,
NCT04622319A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05) (NCT04622319)HER2-Positive Primary Breast Cancer,Residual Invasive Breast CancerRecruiting 
NCT05269004A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis (NCT05269004)Multiple SclerosisRecruiting 
NCT05358717A Study to Evaluate the Safety and Efficacy of PTC518 in Participants With Huntington's Disease (HD) (NCT05358717)Huntington DiseaseRecruiting 
NCT04740918A Study of Trastuzumab Emtansine in Combination With Atezolizumab or Placebo as a Treatment for Participants With Human Epidermal Growth Factor 2 (HER2)-Positive and Programmed Death-ligand 1 (PD-L1)-Positive Locally Advanced (LABC) or Metastatic Breast Cancer (MBC) (NCT04740918)Metastatic Breast CancerRecruiting 
NCT04670016HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers (NCT04670016)DIPG,Brain Tumor, Pediatric, Recurrent,Brain Tumor, DIPG,Radiation Toxicity,Radiation Exposure,Brain Tumor, PediatricRecruiting