Neuf nouveaux projets financés par les Instituts de recherche en santé du Canada (IRSC) dans le cadre de leurs plus récents concours de subventions de fonctionnement et de l’Initiative sur les essais cliniques novateurs de la Stratégie de recherche axée sur le patient sont menés par des chercheurs de L’Hôpital d’Ottawa.
Ces projets, d’une valeur supérieure à 5 millions de dollars, feront avancer les connaissances scientifiques et amélioreront la santé dans des domaines comme l’autisme, les lésions rénales aiguës, la grossesse, les maladies cardiovasculaires, la COVID-19, la chirurgie, la santé mentale et la planification du congé de l’hôpital.
Nos chercheurs codirigent également des subventions administrées par d’autres établissements d’un montant d’au moins 5 millions de dollars.
« Les projets de recherche de ce type nous permettent d’offrir d’excellents soins aux patients tout en réalisant des percées scientifiques qui améliorent la santé à l’échelle mondiale », affirme le Dr Duncan Stewart, vice-président exécutif de la Recherche à L’Hôpital d’Ottawa et professeur à l’Université d’Ottawa.
Les nouvelles subventions comprennent les suivantes :
Subventions accordées dans le cadre du concours Projet des IRSC administrées à l’IRHO
ALbumin To Enhance Recovery after severe Acute Kidney Injury (ALTER-AKI): a multicentre randomized controlled trial - $956,249
- Principal Investigator(s): Edward Clark, Sean M Bagshaw, Jeannie L Callum, Ron Wald
- Co-Investigator(s): Jennifer L Tsang, John G Boyd, Timothy O Ramsay, Dean A Fergusson, Samuel Silver, Alejandro Y Meraz Muñoz, Bram N Rochwerg, Neill K Adhikari, Shannon M Fernando, William Beaubien-Souligny, Emilie Prudence Belley-Côté, Swapnil Hiremath, Rachel Jeong, Josée Bouchard, Rebecca Mathew, Jan Friedrich
Infant and child health outcomes following SARS-CoV-2 infection in pregnancy- $175,000
- Principal Investigator(s): Darine El-Chaâr, Steven Hawken, Jason C Brophy
- Co-Investigator(s): Mark C Walker, William Cameron, Jocelynn L Cook, Daniel J Corsi, Ashraf Kharrat, Katherine A Muldoon, Malia S Murphy, Ryan J Van Lieshout, Robin Ducharme, Sandra I Dunn, Deshayne B Fell, Anne Pham-Huy
Defective endothelial metabolism and mitochondrial biogenesis in autism spectrum disorders - $961,990
- Principal Investigator(s): Baptiste Lacoste
- Co-Investigator(s): Mireille Khacho
REmote cardiac MOnitoring of at-risk SYNCope patients after Emergency Department discharge - A Randomized Controlled Trial: REMOSYNCED- $520,199
- Principal Investigator(s): Venkatesh Thiruganasambandamoorthy
- Co-Investigator(s): Alain Vadeboncoeur, Wadea Tarhuni, Ratika Parkash, Steven C Brooks, Peter Tanuseputro, Eric Mercier, Andrew D Krahn, Monica Taljaard
Multi-Center Implementation of an Educational Program to Improve the Cardiac Arrest Diagnostic Accuracy of Ambulance Telecommunicators and Survival Outcomes for Sudden Cardiac Arrest Victims- $141,526
- Principal Investigator(s): Christian Vaillancourt
- Co-Investigator(s): Katie N Dainty, J. Phillip Nicholson, Judah P Goldstein, Brian E Grunau, Shannon Leduc, Sheldon Cheskes, Matthew N Church, Venkatesh Thiruganasambandamoorthy, James M Christenson, Michael Feldman, Monica Taljaard, Ian Blanchard, Sandra E Jenneson
Piloting the EAGER trial: Expectant management versus induction At 38 weeks among individuals with GEstational diabetes mellitus - a Randomized controlled trial- $ 569,926
- Principal Investigator(s): Mark Walker, Darine El-Chaâr, Elizabeth V Asztalos, Dean A Fergusson, Denice S Feig
- Co-Investigator(s): Malia S Murphy, Erin J Keely, Steven Hawken, Shi Wu Wen, Graeme N Smith, Daniel J Corsi, Katherine A Muldoon, Alysha Harvey, Ruth Rennicks White, Howard Berger, Jocelynn L Cook, Jon Barrett, Kednapa Thavorn, Kellie E Murphy, Laura M Gaudet, Mathew Sermer, Ravi R Retnakaran, Rohan D D'Souza, Francois Audibert, Prakeshkumar Shah, Nir Melamed, Evelyne E Rey, Emmanuel Bujold, Michael E Helewa, Haim A Abenhaim, Kenneth Lim, Stephen L Wood, Christy Pylypjuk
Subventions accordées dans le cadre du concours Projet des IRSC avec des chercheurs principaux de l’IRHO – administrées dans un autre établissement
BRAINapt: TBI International Adaptive Platform Trial - $4,846,275
- Principal Investigator(s): Alexis F Turgeon. Shane William English, François Lauzier, Michelle McDonald, Lynne Moore, Jay Park, Ryan Zarychanski
- Co-Investigator(s): I. Ball. E. Belley-Côté, J. Boyd, K. Burns, M. Bérubé, D. Clarke, F. D'Aragon, A. Docherty, D. Fergusson, R. Fowler, C. Francoeur, R. Green, D. Griesdale, A. Kramer, D. Kutsogiannis, F. Lamontagne, V. Lau Madame, Lessard Bonaventure, L. Malbouisson, J. Marshall, V. McCredie, C. Mcarthur, J. Mejia-Mantilla, D. Menon, A. Nichol, S. Nicholls, J. Rhodes, A. Rigamonti, D. Scales, M. Sekhon, S. Sharma, M. Slessarev, M. St-Onge, E. Sy, L. Terrett, M. Verret, S. Webb, N. Yada, F. Zeiler
- Note: this grant is administered at Université Laval
Psilocybin Assisted Therapy (PAT) for Treatment Resistant Depression in Bipolar II Disorder (TRD.BD-II): A Randomized Controlled Trial - $1,200,076
- Principal Investigator(s): Yatham, Lakshmi N; Ha, Kyooseob; Husain, Muhammad I; Keramatian, Kamyar; Rosenblat, Joshua D; Saraf, Gayatri
- Co-Investigator(s): Aaronson, Scott T; Chakrabarty, Trisha; Fiedorowicz, Jess G; Frangou, Sophia; Hatcher, Simon; Lam, Raymond W; Menon, Mahesh; Michalak, Erin; Solmi, Marco; Torres, Ivan; Williams, Monnica; Wong, Hubert H; Woolley, Joshua
- Note: this grant is administered at the University of British Columbia
Subventions accordées dans le cadre du concours de l’Initiative sur les essais cliniques novateurs de la Stratégie de recherche axée sur le patient des IRSC administrées à l’IRHO
- Principal Investigator(s): Aucoin, Sylvie D; Forster, Alan J; Kidd, Gurlavine D; Lalu, Manoj M; McIsaac, Daniel I
- Co-Investigator(s): Hladkowicz, Emily
Pilot trial of time restricted eating to support an adaptive innovative clinical trial of combined chronotherapies for mania in bipolar disorder - $191,811
- Principal Investigator(s): Fiedorowicz, Jess G; Saraf, Gayatri; Solmi, Marco; Ward-King, Jessica
- Co-Investigator(s): Audet, Marie-Claude; Dargél, Aroldo A; Robillard, Rébecca
Improving discharges of people experiencing homelessness from hospital: a quality improvement project embedded in a stepped wedge design - $196,807
- Principal Investigator(s): Hatcher, Simon; Forster, Alan J; Van Herk, Kimberley; White, Tracy
- Co-Investigator(s): Fiedorowicz, Jess G; Patel, Rakesh V; Ayonrinde, Oyedeji; Beder, Michaela; Masters, Christina; Nicholls, Stuart G; Ramsay, Timothy O; Simmons, John G
These projects are supported by core resources for research at The Ottawa Hospital, such as the Ottawa Methods Centre.
The Ottawa Hospital is a leading academic health, research and learning hospital proudly affiliated with the University of Ottawa and supported by The Ottawa Hospital Foundation. Learn more about how research is funded.
